CONSELF | Healthcare
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When dealing with people’s health, there is no room for risk. Deadlines and safety standards become strict rules and virtual simulations can be a game changer in design requirements compliance.


Simulations of worst-case scenarios can be performed in order to improve design and production process reliability, which in turns means easier compliance with regulations, i.e. more lives saved. Especially with a growing demand of new therapies by the market, which is starting to focus on pathology affecting a small population.


With this approach, successful healthcare products that are both affordable for the patients and profitable for the companies can be obtained. The advantage of simulations is strategic: via testing in virtual environment, researchers can identify the best solutions in the very early stages of the research, lowering costs.


Many different applications are possible for modern simulation tools, here are some examples:


  • Mixing: multi-phase flows can be simulated to study phases dispersed randomly in stirred tanks, static mixers, homogenizers and emulsifiers.
  • Granular flows/Solids handling: Discrete Element Modeling (DEM) capability allows to simulate the motion of a large number of interacting discrete particles, tracking the interaction between every particle in a numerically efficient manner: to do so, contact forces and energy transfer due to collision and heat transfer between particles are modeled. It can be applied to improve uniformity of tablet coating, chaotic movement of particles in fluidized beds analysis,  or filter particles in medical devices.
  • Fluid-Structure interaction: typical applications range from blood vessels analysis (coronary or carotid artery), respiratory/lung, heart valve and aneurysm applications to models of blood pumps.

In medical and pharmaceutical manufacturing sector contaminant monitoring is of paramount importance inside production plants facilities and clean rooms. By means of CFD simulations it is possible to have detailed insights on how these species diffuse from their sources and spread into the local area. Contaminant concentration can be simulated in all its configurations: from liquid through pipes to HVAC systems, with no limits on the species flow and on the physics to be modeled.

Flow through ducts, vessels and pipes can be successfully simulated by means of CFD software. A lot of relevant quantities can be studied via non invasive techniques as digital images coupled with numerical solutions for fluid motion. In the medical sector it can be very useful, in fact, it allows to assess patient disease progression as well as response to a particular treatment in terms of measurable quantities.